In models of acute liver injury, it attenuates ferroptosis via activation of the AMPK/sequestosome 1/NRF2 pathway (Zhang H. et al., 2025), while in cardiomyocytes, ferroptosis is suppressed through downregulation of lipocalin 2 (LCN2) (Zhang et al., 2025b). Here, LCN2 is linked to injury.