Correlations between Warburg-associated proteins and immune infiltration underscore these effects: GLUT1 and LDH5 inversely correlate with CD8+/CD3+ T cells in renal cell carcinoma, MCT4 enhances dendritic and macrophage presence but reduces B cell infiltration in breast cancer, and PKM2 dampens CD8+ T cell function [123,124]. Here, CD8A is linked to hereditary clear cell renal cell carcinoma.