Current theories propose that KE ingestion can acutely lower blood glucose and shift substrate utilization toward greater carbohydrate oxidation (CarbOx) and reduced FatOx (Fernández‐Verdejo et al., 2023), which may be particularly beneficial for individuals with MetS who often exhibit impaired insulin sensitivity and reduced mitochondrial efficiency (Prasun, 2020; Ruderman et al., 2013). The gene discussed is INS; the disease is metabolic syndrome.