ATM and infection: Although monocytic THP-1 cells were infected with the same bacterial burden of CFT073, CFT073ΔtcpC or CFT073ΔtcpC + pASK-IBA5plus-TcpC (Fig. 7E), Atc attenuated bacterial replication dose-dependently during the infection period thereby presumably reducing the stimulatory potential of the culture (Fig. 7E, F).