TNF and infection: Infection of monocytic THP-1 cells with CFT073ΔtcpC + pASK-IBA5plus-TcpC and titrated induction of the plasmid demonstrated that the expression level of TcpC achieved statistically significant higher IL-1β amounts with 5 to 15 ng/ml of Atc compared to CFT073ΔtcpC (Fig. 7C), while TNFα amounts were slightly but significantly increased (Fig. 7D).