Transcriptional programs associated with c-myc, PI3K/AKT/mTOR, and cell proliferation were observed in PTCL and in CTCL with LCT in independent bulk RNA-seq (Fig. 1A) and scRNA-seq (Fig. 1B) datasets. The gene discussed is AKT1; the disease is mature T-cell and NK-cell non-Hodgkin lymphoma.