At the clinical prognostic level, since existing studies have confirmed that TIL-Bs have positive prognostic significance in most cancers, this directly explains the phenomenon observed in the present study—significantly shortened OS in cervical cancer patients with high NOTCH1 expression and indirectly verifies that NOTCH1 may regulate tumor prognosis by affecting TIL-B function. The gene discussed is NOTCH1; the disease is cancer.