KLRK1 and neoplasm: It should be noted that the capacity of senescent cells of attracting NK cells within the TME can also affect the non-senescent cell compartment, as not senescent tumor cells are targeted by NK cells, and activated T cells can become susceptible to autologous NK lysis via NKG2D/NKG2D ligand interaction through granule exocytosis leading to inflammation quenching (182).