According to the European Group for the Immunological Classification of Leukemias (EGIL) scoring system, surface antigen expression is considered positive when ≥20% of blasts exceed the control cutoff, while cytoplasmic markers such as myeloperoxidase (MPO), cytoplasmic CD79a (cCD79a), terminal deoxynucleotidyl transferase (TdT), and cytoplasmic CD3 (cCD3) require a ≥10% threshold [9-11]. This evidence concerns the gene MPO and leukemia.