CELF1 and central nervous system cancer: Several studies have revealed that CELF1 demonstrates frequent upregulation in glioma, oral squamous-cell carcinomas, and hepatocellular carcinoma (Xia et al., 2015; Talwar et al., 2013; Kim et al., 2017), and its oncogenic properties make it a crucial target for influencing cell proliferation and growth and precisely regulating the cell cycle.