ADA and proctitis: Regarding positive signals, the strongest ones were adenosine deaminase decreased (n = 4), large intestine erosion (n = 7), ileocaecal resection (n = 4), ileal ulcer (n = 8), and proctitis ulcerative (n = 3) (Supplementary Figures S1–S3; Supplementary Tables S1–S4).