In ARDS samples, ROC analysis of the training cohort yielded AUC-ROC values for LCN2, AIF1L, STAT3, SOCS3 and SDHD of 0.814, 0.791, 0.819, 0.824 and 0.815, respectively (Figure 5A). The gene discussed is STAT3; the disease is acute respiratory distress syndrome.