ESX1 and infection: CRISPR-based epitranscriptomic editors (dCas13-METTL3, dCas13-ALKBH5, etc.)or metabolic labelling followed by miCLIP were not employed to confirm the exact modified residues, nor were infections performed with Mtb mutants lacking ESX-1 or other RNA-binding effectors to test whether the observed shifts are microbe-driven.