Consistently, flow cytometry analysis indicated that macrophages were skewed toward the M1 phenotype, as indicated by increased percentages of CD11b+F4/80+CD86+ cells and reduced percentages of CD11b+F4/80+CD206+ cells in syngeneic tumor tissues of the RAW264.7PRDX1‐KD group compared to the RAW264.7CON‐KD control group (Figure 8B). The gene discussed is MRC1; the disease is neoplasm.