MKI67 and neoplasm: Additionally, the Ki-67 high-expression group showed a significantly greater number of L1CAM+ T-CTCs (5.02 ± 6.989) compared to the low-expression group (2.51 ± 4.726, p = 0.042; Figure 4C), suggesting that L1CAM+ T-CTCs may be associated with tumor cell proliferative activity.