SDHB and bone metastasis: Univariable analysis revealed that the factors significantly associated with shorter bone metastasis-free survival were EAPGL (HR, 3.701 [95% CI, 1.786–7.670]; P =0.000), lower 24h U-NE concentrations (HR, 0.998 [95% CI, 0.996–1.000]; P =0.029), and SDHB mutation (HR, 5.270 [95% CI, 0.190–0.088]; P =0.000).