Based on the bioinformatic analysis data from the TargetScanHuman (McGeary et al., 2019) and miRDB target (Chen and Wang, 2020) prediction algorithms, 4 candidate target genes of miR-495, ELOVL7, IGF1R, TNFRSF1B and NRF2, were selected for experimental validation due to their previously reported involvement in pathways related to the AD pathophysiology. This evidence concerns the gene IGF1R and Alzheimer disease.