Impaired expression of specific miRNAs has been linked to increase Aβ formation (Liu et al., 2012; Zhao et al., 2017), Tau phosphorylation (Wang et al., 2016), synaptic dysfunction (Xu et al., 2019), oxidative stress (Nunomura and Perry, 2020) and neuroinflammation (Li et al., 2024) among other pathways related to AD. The gene discussed is MAPT; the disease is Alzheimer disease.