Polysaccharides isolated from A. carmichaeli modulate gut communities including Bacteroides, Dubosiella, Alistipes, and Prevotella, restore short‐chain fatty acid production, and exhibit anti‐inflammatory effects via inhibition of NOD1 and TLR4 pathways, improving gut barrier integrity in DSS‐induced colitis models (Fu et al. 2022). Here, TLR4 is linked to colitis.