NHSL3 and cancer: KIAA1522 has been reported to promote cancer proliferation, migration, invasion, and metastasis through key pathways such as Wnt/β-catenin, ERK, Notch, and various lncRNA/circRNA–microRNA axes (Fan et al., 2022; Guo et al., 2020; Hu et al., 2021; Jiang et al., 2020; Lin et al., 2021; Xie et al., 2017; Yi et al., 2022).