Notably, SLC7A11 is highly expressed in lung, liver, pancreatic, and breast cancers, suggesting its potential role in tumor proliferation, metastasis, and chemotherapy resistance.[17] Similarly, LRPPRC is involved in mitochondrial function and is upregulated in gastric cancer, hepatocellular carcinoma, and lung adenocarcinoma.[18–20] the roles of disulfidptosis-related genes in CC remain poorly understood. Here, LRPPRC is linked to breast cancer.