In the liver metastasis group, the mean age of patients was 61.1 ± 13.2, the majority were male, most had TMB < 10, and the main tumor types included NSCLC, melanoma, and colorectal cancer, and PD-1/PD-L1 (70.5%) was the main treatment (Table 1). The gene discussed is PDCD1; the disease is melanoma.