CRP and endothelial dysfunction: Elevated NLR, monocyte counts, and CRP levels in early pregnancy have been repeatedly identified as markers of increased inflammatory responses, which are believed to play a crucial role in the pathophysiology of PE.[21–23] Several studies have highlighted the role of inflammation in endothelial dysfunction and impaired vascular remodeling, which are central to PE development.[10,24] Similarly, elevated CRP levels in PE patients, as observed in our study, have been previously associated with poor pregnancy outcomes and have been suggested as potential biomarkers for PE prediction.[25]