In order to test whether high doses of gonadosteroids also induce increased expression of co-receptors playing a significant role in HIV-1 infection, we studied co-receptors expression (in particular, CCR5, and CCR8) in uninfected donor’s PBMCs after treatment with high doses of hormones, post infection and in infected PBMCs treated with hormones (Supplementary File Figure S2). The gene discussed is CCR8; the disease is infection.