Given all this, it is not surprising that BIRC6 overexpression has been reported in many types of cancer, including triple-negative breast cancer, prostate, kidney, colorectal, pediatric acute myeloid leukemia, ovarian cancer, hepatocellular carcinoma, esophageal squamous cell carcinoma and non-small cell lung cancer (NSCLC) [28,29,30,31,32,67,68]. This evidence concerns the gene BIRC6 and hepatocellular carcinoma.