BIRC5 and Familial prostate cancer: In line with these findings, Wang et al. (2011) reported that YM155 triggers autophagy-dependent apoptosis in prostate cancer cells [39], while Danielpour et al. (2019) demonstrated that it suppresses mTORC1 activity via AMPK activation, reinforcing its role as a broader stress-response modulator beyond survivin inhibition [40].