Complementing this, Shipunova et al. (2021) decorated pre-formed poly(lactic-co-glycolic acid) (PLGA) nanoparticles with anti-HER2 affibodies post-assembly for targeted delivery of photosensitizers, inducing photoactivated cell death upon light irradiation in HER2-positive breast cancer cells with high specificity and minimal off-target effects [65]. Here, ERBB2 is linked to breast carcinoma.