BTG3 and systemic lupus erythematosus: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease affecting multiple systems, with its pathogenesis centered on the aberrant activation of autoreactive B cells and the excessive production of pathogenic autoantibodies, such as anti-nuclear antibodies (ANA) and anti-double-stranded DNA antibodies (anti-dsDNA) [1].