Treatment with CB + miR + R/PGA-SLN-CSW increased cytotoxic (CD8+) and helper (CD4+) T cell populations, reduced FoxP3+ regulatory T cells, and depleted CD206+ M2-type TAMs within the tumor and/or spleen (Figure 5A–M and Figure S8–S11). The gene discussed is FOXP3; the disease is neoplasm.