Another neuro-degenerative disease, such as Parkinson’s Disease (PD), is characterized by the aggregation of misfolded alpha-synuclein protein in the brain that leads to the formation of Lewy bodies, which eventually leads to the degeneration of dopaminergic regions in the substantia nigra (a critical brain region for the production of dopamine [81]). This evidence concerns the gene SNCA and Parkinson disease.