CD40LG and leptospirosis: However, no significant differences were observed between the IgM-detecting POC tests at any time point (p-values ≥ 0.205), apart from Test-itTM Leptospirosis (Life Assay) in week 2 in comparison to WITNESS® (p = 0.011) and to FASTest® (p = 0.045) (Table 7).