Indeed, about 70% of the mice with gastric lesions had intraepithelial neoplasia, and the overgrowth of Lactobacillus murinus ASF361 correlated with enhanced gastric inflammation and the expression of cancer-related factors, such as TNF-α, Ptger4, and TGF-β [24]. This evidence concerns the gene TNF and intraepithelial neoplasia.