In type 1 diabetes, the T-cell-mediated autoimmune process is usually started early in life and marked by the production of β-cell-specific autoantibodies such as islet cell antibodies (ICA), glutamic acid carboxylase autoantibodies (GADA), insulin autoantibodies (IAA), and autoantibodies against zinc transporter 8 (ZnT8A), with risk increasing with the number of positive antibodies [10]. The gene discussed is INS; the disease is type 1 diabetes mellitus.