PON1 and Renal insufficiency: Therefore, we performed a case–control, cross-sectional study comparing the levels of eight adipokine-related markers (adiponectin, leptin, resistin, chemerin, adipsin, thrombospondin-1 [TSP-1], paraoxonase-1 [PON-1], and myeloperoxidase [MPO]) in MM patients and healthy controls and evaluated their associations with established prognostic parameters, disease stage, treatment response, and CRAB criteria (hypercalcaemia, renal failure, anemia, and bone lesions).