Several types of immune cells were identified, each with a different role in defense mechanisms: immune cytotoxic CD8+ T cells, CD4+ T cells, natural killer cells (NK cells), B lymphocytes, dendritic cells, tumor-associated macrophages (TAMs), myeloid-derived suppressor cells (MDSCs), and regulatory T cells (Treg cells) [27]. This evidence concerns the gene CD4 and neoplasm.