Transfection of plasmid constructs containing the pre-miR-34a sequence with the G or A-rs72631823 allele into INS-1 (rat insulinoma) and MIN6 (mouse insulinoma) cell lines showed increased expression of miR-34a with the A allele in all cell lines compared to the G allele. Here, FOXM1 is linked to pancreatic insulinoma.