Hematological and neurological expressed 1-like (HN1L) acts in concert with Activator Protein-2 gamma (AP-2γ) to promote the transcription of methyltransferase 13, (METTL13), which then cooperates with MYC to transcriptionally upregulate the expression of ZEB1 in HCC cells [36]. Here, JPT2 is linked to hepatocellular carcinoma.