The expression of FADD, MLKL, TLR2, PGAM, HMGB1, CXCL 1, TRAF2, and EZH2 was elevated in CRC cells, in contrast to FAS, RIPK1, RIPK3, TLR3, TNFRSF, ALDH2, and NDRG2, which presented increased expression in healthy intestinal cells. The gene discussed is TRAF2; the disease is colorectal carcinoma.