In the two comparison groups, 15 genes were commonly overexpressed in CRC SCs with liver metastasis, namely A1BG, ADRA1A, ANKS3, APOC2, C4BPA, DNER, ETDC, EVI2A, F2, FAM71E2, FGG, IDO2, PLA2G4C, SALL1, and TMC3. The gene discussed is F2; the disease is colorectal carcinoma.