By consulting the UALCAN and Human Protein Atlas databases, we found that BIRC5 (survivin), BIRC2, and CASP6 (all downregulated by HCQ in Ca9-22 cells) are overexpressed in head and neck squamous cell carcinoma (HNSCC) tissues compared to normal tissues, with expression levels increasing across tumor stages. Here, BIRC2 is linked to head and neck squamous cell carcinoma.