PRDX2 and type 2 diabetes mellitus: This analysis indicates that the transcriptomic profile of T2DM β-cells deviates from the normal maturation trajectory, reverting toward an immature neonatal and early childhood state, as exemplified by the expression levels of characteristic genes such as Calcyphosine (CAPS) and Peroxiredoxin 2 (PRDX2)—antioxidant and stress response genes—that are restored to neonatal levels.