ACE and hydrops fetalis: Treatment strategies may involve: no specific therapy, only symptomatic management (infusions, antipyretics), antibiotics, HF and antiarrhythmic therapy with beta-blockers, or a combination of optimal HF therapies such as ACE inhibitors, angiotensin II receptor blockers (ARBs), mineralocorticoid receptor antagonists (MRAs), diuretics, and other agents [5,7,23].