By contrast, Protein YIPF3 (Protein YIPF3) with a log2 fold change of −3.39 (95% CI: −6.67–−0.11, nominal p = 0.04), Kallikrein-1 (KLK1) with a log2 fold change of −3.39 (−5.87–−0.91, nominal p = 0.01) and Charged multivesicular body protein 5 (CHMP5) with a log2 fold change of −2.63 (95% CI: −4.72–−0.54, nominal p = 0.017) showed the lowest average abundance in AKI patients compared to non-AKI patients. The gene discussed is CHMP5; the disease is acute kidney injury.