In multivariate logistic regression, independent predictors of APE were: age (OR 1.06, 95% CI 1.02–1.10, p = 0.004), hypertension (OR 2.94, 95% CI 1.24–6.97, p = 0.014), NT-proBNP (OR 1.0003 per pg/mL, 95% CI 1.0001–1.0006, p = 0.008), and IL-6 (OR 1.012 per pg/mL, 95% CI 1.002–1.022, p = 0.019). The gene discussed is IL6; the disease is Hypertension.