POU5F1 and Borderline personality disorder: Several X-chromosomal CpGs (e.g., in PQBP1, ZNF41, RPL10) and one on chr6 (TAP2) lower methylation in BPD. Hypomethylation differences were amplified in BPD subjects with childhood trauma. Additionally, four autosomal genes (e.g., POU5F1, GGT6) were differentially methylated depending on trauma history.