Statistically significant differences were observed among the 3 groups in terms of age, SBP, all severity scores, laboratory parameters (including Hb, RBC, BUN and BUNCR), comorbidities (including CCI, Sepsis, Hypertension and Liver cirrhosis), treatment (including MV), and ACM of 28-day, 90-day and 1-year (all p < 0.01). The gene discussed is GSTM1; the disease is hypertensive disorder.