Baseline characteristics (age, sex, hemoglobin, white blood cell counts, bone marrow cellularity, and normal karyotype frequency) showed no significant differences between AML and MDS patients with germline DDX41 variants (all p > 0.05), except for lower platelet counts in AML (p = 0.025) (Table 1). This evidence concerns the gene DDX41 and myelodysplastic syndrome.