Molecular studies have revealed that B. mori employs an innate immune system comprising pattern recognition receptors (PRRs), immune signaling cascades (JAK/STAT, Toll, and IMD), antimicrobial peptides (AMPs), RNA interference (RNAi), and cellular responses like phagocytosis and melanization to combat bacterial and viral infections [23,28]. Here, SOAT1 is linked to viral infectious disease.