Additionally, elevated circulating levels of adipocyte fatty acid-binding protein (AFABP), fibroblast growth factor 21, and pigment epithelium-derived factor are positively correlated with markers of metabolic syndrome and microvascular complications, including the progression of nephropathy in Chinese patients with T2DM [315,316,317,318]. The gene discussed is FABP4; the disease is type 2 diabetes mellitus.