In recent years, non-standard inflammatory indices such as systemic immune-inflammation index (SII), neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), monocyte/lymphocyte ratio (MLR), C-reactive protein/albumin ratio (CRP/Alb) and Fibrosis-4 score (FIB-4) have gained increasing attention, particularly for the early detection of metabolic and hepatic disorders. This evidence concerns the gene ALB and fibrosis.