A 75-year-old patient scheduled for arthroplasty with preoperative anemia (hemoglobin < 10 g/dL), baseline CRP of 8 mg/L, ASA score of 3, and 1.5-day preoperative delay would have:Age = ln(75) = 4.32, CRP = ln(8) = 2.08, Delay = ln(1.5) = 0.41, Anemia = 1, ASA_score = 3. The gene discussed is CRP; the disease is anemia.