However, Satar et al. evaluated 83 premature infants with and without PPROM and they showed that while maternal serum IL-6 was significantly higher in the PPROM group (p < 0.01), there was no difference between UC IL-6 levels between groups (p > 0.05), and no association was observed between IL-6 and RDS or BPD [45]. This evidence concerns the gene IL6 and newborn respiratory distress syndrome.